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Bruker announces developments for highly multiplexed spatial proteomics and multiomic tissue imaging at large field-of-view

7 June 2022 | Product
by Ian Michael

Bruker has announced new developments for spatial multiomics of tissue and tumour microenvironments (TME). Following Bruker’s strategic partnership with AmberGen, enhancements have been introduced for MALDI HiPLEX-IHC mass spectrometry imaging. MALDI HiPLEX-IHC represents a breakthrough in multiomics imaging by combining targeted protein expression spatial profiling with unbiased small molecule MALDI imaging to co-localise proteins and small molecules such as glycans, lipids, metabolites or xenobiotics. Using AmberGen’s Miralys™ antibody-based photocleavable peptide mass tags, highly multiplexed IHC staining and photocleavage of peptide markers fit seamlessly into Bruker’s IntelliSlide®-based automated workflows for MALDI imaging.