SCIEX has introduced Biologics Explorer software, for the analysis of high-resolution protein characterisation data, and to enable decisions to be reached on the most important quality attributes for biopharmaceuticals. To bring protein therapeutics to market safely and rapidly, it is critical to fully characterise candidate molecules at every stage of development. Biologics Explorer allows scientists to harness the potential of the rich spectra produced from the Zeno trap and electron activated dissociation (EAD) of the ZenoTOF 7600 system. The results it produces are based upon a nodal algorithm structure that enables each processing and analysis step to be optimised. Currently available workflows include intact and subunit analysis, PTM determination and MAM, peptide mapping by EAD or CID and disulfide bond analysis.
Biologics Explorer has come about due to a software partnership between SCIEX and Genedata. The software is built upon Genedata Expressionist®, an enterprise software platform for biopharmaceutical mass spectrometry.