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MS Imaging News

Scientists from the Skolkovo Institute of Science and Technology (Skoltech) have proposed a mass spectrometry imaging (MSI) method making use of the unique features of human vision.

Researchers from Osaka University have developed a new MSI method for brain tissue analysis in high spatial resolution that requires no sample preparation.

The new matrix-assisted ionisation in vacuum (MAIV) technique has been used to generate mass spectrometry images for the first time. The technique’s ability to generate multiply charged ions from peptides and proteins facilitates their identification by tandem mass spectrometry.

By measuring the height profile of the sample prior to analysis, mass spectrometry imaging can now visualise the distribution of chemical substances on samples with non-flat surfaces.

University of Alabama at Birmingham, USA, researchers have made a microscopic snapshot of the early renal lipid changes in acute kidney injury, using matrix-assisted laser desorption/ionisation (MALDI) tissue imaging to localise the changes.

Researchers have used mass spectrometry imaging to uncover exactly how a human egg captures an incoming sperm to begin the fertilisation process.