Spectroscopy Since 1975


Analysis and sequencing of nucleic acids by matrix-assisted laser desorption/ionisation mass spectrometry

Marek Šebela

This article gives a most useful overview of the analysis and sequencing of nucleic acids by matrix-assisted laser desorption/ionisation mass spectrometry, which should interest all readers and may well serve as a useful tutorial article.

Article  |  Issue 28/5 (2016)

Molecular imaging by mass spectrometry: application to forensics

Tiffany Porta, Emmanuel Varesio, Thomas Kraemer, Gérard Hopfgartner

After an introduction to MALDI, DESI and SIMS, the authors describe their main applications in forensics, as well as the advantages provided in terms of sample preparation over approaches routinely used in toxicological laboratories.

Article  |  Issue 23/5 (2011)

Natural rubber latex gloves: identifying and localising allergens applying mass spectrometric methods

Martina Marchetti-Deschmann, Günter Allmaier

This article shows that MALDI high resolution mass spectrometry demonstrated directly that Hev b 6 and Hev b 1, and also truncated forms thereof, are present on the inner surface of medical NRL gloves. The speed and high accuracy of the applied method and instrumentation makes the detection of surface associated proteins feasible without any prior protein extraction procedure (in situ localisation).

Article  |  Issue 21/4 (2009)

Species origin identification of Oetzi's clothing by MALDI-ToF mass spectrometry using tryptic hair digests

Klaus Hollemeyer, Wolfgang Altmeyer, Elmar Heinzle, Christian Pitra

In 2007 we introduced our method in Spectroscopy Europe describing the identification of furs by hair digest based matrix-assisted laser desorption/ionisation time of flight (MALDI-ToF) mass spectrometry (MS). This so-called SIAM (Species Identification of Animals) method can also be used for the species determination of ancient furs.

Article  |  Issue 21/2 (2009)

The role of MALDI-enabled linear ion trap mass spectrometry as a sensitive tool in tissue imaging

Maria C. Prieto Conaway, Shousong Cao, Farukh Durrani, Youcef Rustum, Ping Wang, Khin Marlarc, Latif Kazim

This article discusses matrix-assisted laser desorption/ionisation (MALDI) enabled linear ion trap (LIT) mass spectrometry (MS) as a technique for fast and accurate tissue imaging, compared to the more traditional time-of-flight (ToF) method.

Article  |  Issue 20/6 (2008)

Identification of furs of domestic dog, raccoon dog, rabbit and domestic cat by hair analysis using MALDI-ToF mass spectrometry

Klaus Hollemeyer, Wolfgang Altmeyer, Elmar Heinzle

The authors show how the use of SIAM method (Species Identification of Animals MALDI-TOF mass spectrometry) is a fast and reliable tool for recognising the origin of mammalian species.

Article  |  Issue 19/2 (2007)