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Waters Xevo G2 QTof Mass Spectrometer

Xevo G2 QTof is a next-generation benchtop exact mass MS/MS mass spectrometer and is the first Xevo time-of-flight mass spectrometer to feature Waters QuanTof technology, currently only available with Waters SYNAPT G2 MS and G2 HDMS mass spectrometers. This technology brings research-grade quantitative and qualitative analytical performance to research, academic and industrial laboratories. QuanTof technology can extend the dynamic range of previous generation Xevo QTof systems to greater than four orders of magnitude and results in much higher mass resolution (20,000 FWHM) for greater efficiency and productivity in the laboratory.

Combined with Waters ACQUITY UPLC System, the Xevo G2 QTof uses the power of UPLC/MSE, a simple, patented, method of data acquisition that comprehensively catalogues complex samples in a single analysis. This gives scientists a comprehensive digital record of the sample that can be re-interrogated at will, eliminating the need to re-analyse the sample which scientists often have to do when, for example, using labelled approaches of “data directed” protein quantification.

The Xevo G2 QTof is designed for labs driven by the need to produce accurate quantitative and qualitative information on increasingly large numbers of samples when doing intact protein analysis, peptide mapping, oligonucleotide analysis, metabolite identification, metabolite profiling, proteomics experiments and food safety screening.

“The Xevo G2 QTof outperforms in many aspects,” says Dr George Keenan of SASA, Edinburgh, Scotland, a scientist who has developed sub-ten minute UPLC/MS/MS methods for surveillance monitoring of as many as 160 different pesticides in fruits and vegetables and whose laboratory is one of the highest ranking in Europe on proficiency tests administered by the European Union Community Reference Labs Survey. “Its resolution and precision are significantly superior to earlier generation quadrupole time-of-flight instruments and it has the sensitivity our lab requires for analysing foods for compliance monitoring with EU regulations.”

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