Shimadzu has introduced the LCMS-2050, a single quadrupole LC/MS detector. It is equipped with the newly developed Heated Dual Ion Source (DUIS) as standard. This hybrid source is a combination of electrospray ionisation (ESI) and chemical ionisation at atmospheric pressure (APCI). In this way, ions that ionise well either by APCI or ESI can be detected simultaneously. The result is high sensitivity to compounds in a wide range of chemical properties, including low-polar compounds. By quickly switching the polarity, it is also possible to determine both positive and negative ions during the measurement with high sensitivity. With the help of Shimadzu’s MASS-IT function for displaying mass information, complex data can be collected at a glance. The function detects and superimposes the signature mass information on the LC-UV or LC-PDA chromatogram. With just one click, several components in a single UV peak become visible as well as “hidden” components without UV absorption.