908 Devices have introduced a new Oligos assay kit for its ZipChip device that enables fast and accurate identification and quantitation of oligonucleotides. Using this new Oligos kit with the ZipChip device provides an easy method for high-resolution separation and mass spec sample introduction without the use of harsh ion-pairing reagents. Traditional liquid chromatography workflows for oligonucleotide analysis can be cumbersome and slow, and the use of ion-pairing reagents leads to frequent mass spectrometry instrument maintenance and downtime. ZipChip integrates with Thermo Fisher, Sciex and Bruker mass spectrometers and uses microfluidic-based Capillary Electrophoresis and electrospray ionisation to minimise sample preparation, perform high-resolution separations and directly introduce samples into a mass spectrometer.
Oligos kit for ZipChip CE-MS device
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