Spectroscopy Since 1975

Multi-nuclear PFG spectroscopy on a benchtop NMR spectrometer

Molecular diffusion is the mechanism that defines molecular mobility in solutions. The study of diffusion processes is of interest in widespread fields in science where transport of mass needs to be determined. NMR is the method of choice to quickly determine self-diffusion coefficients of chemical species in solution. A commonly used NMR technique requires the combination of pulsed field gradients with a stimulated echo sequence (PGSTE). The spectroscopically resolved version of this sequence makes it possible to measure the diffusion coefficient of different molecules in a mixture by measuring the diffusion attenuation of the signal of each particular chemical group of each molecular structure.