Metabolomics Workflow

Thermo Fisher Scientific has announced a new workflow to aid analytical and informatics challenges in metabolomics. The workflow integrates new applications software—SIEVE 2.0 differential expression analysis and Mass Frontier 7.0 structural elucidation software—with new HRAM instruments, the Q Exactive benchtop quadrupole-Orbitrap LC-MS/MS and the Orbitrap Elite hybrid mass spectrometer. SIEVE software is an automated solution for label-free, semi-quantitative differential expression analysis of proteins, peptides and metabolites. Mass Frontier software offers an MSn spectral data interpretation solution for identifying challenging differentially expressed components in metabolomics studies with many features including comprehensive spectral data and fragmentation–mechanism knowledge management. The mass spectrometers provide the level of resolution necessary to resolve the many compounds found in biological matrices and the accuracy needed to identify compounds.



Thermo Fisher Scientific
Issue: 23-04
RSN: 104
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