Biocius Life Sciences and Agilent Technologies have launched the RF360 high-resolution system for high-throughput screening of in vitro ADME assays. RapidFire technology, combined with Agilent’s ToF mass spectrometers, enable a wide range of ADME assays, including drug–drug interaction, metabolic stability, Caco, PAMPA and others. When performing such assays with the RF360, a priori knowledge of the test compound is not required, as data is acquired in full scan ToF-MS mode. Post acquisition, the relevant data is extracted using RapidFire software, eliminating the time-consuming and labour-intensive steps of LC-MS method development and batch analysis.

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