Professor Pauline Rudd, of the National Institute for Bioprocessing Research and Training (NIBRT) in Dublin, Ireland, has received an Agilent Thought Leader Award in support of her emerging glycomics research. The award includes a grant of funding and instruments to the NIBRT. The goals of the research are to develop novel approaches to analyse protein glycosylation which will assist in the characterisation of recombinant protein drugs, and to study potential glycan biomarkers associated with disease using liquid chromatography/mass spectrometry.
A new technique to analyse fingermarks from crime scenes has the potential to give crucial additional details about a suspect such as their medications, diet, the time at which they accidentally left the fingermark and can even be used to detect any substances they might have touched, such as traces of cocaine. These extra details can be important background information in a criminal investigation, especially if the suspect's fingerprint is not on the police database. It is hoped the technique will compliment current fingermark detection techniques and assist in criminal investigations.
The US Army Research Laboratory is working on laser-induced breakdown spectroscopy (LIBS), which has shown significant advances since its inception in the 1980s. Today, LIBS technology is used for multiple purposes, including the 2011 mission to Mars, detection of chemical, biological, radiological, nuclear and explosive (CBRNE) material, and materials matching in forensic cases.
Raman spectroscopy has been used to show that graphene has the potential to replace carbon fibres in high performance materials that are used to build aircraft. Graphene—discovered in 2004 by physicists Professor Andre Geim and Dr Kostya Novoselov at The University of Manchester—is a two-dimensional layer of carbon atoms that resembles chicken wire.
The Doppler effect is of fundamental importance in laser spectroscopy. The atoms and molecules in the ensemble under observation perform continuously movements with velocities grouped around one central frequency value which is determined by the ensemble’s temperature. This temperature movement of atoms leads to a spectral broadening of the transitions and so limits the application of many devices and methodologies. For atoms enclosed in cells with centimetre-scale size, the laser beam “sees” the atomic ensemble in the same way—with the same velocity distribution of atoms independently of the propagation direction trough the cell. In this case we say that the velocity distribution of atoms is spatially isotropic.
A new mass spectrometry-based method allows the identification of N-glycosylated protein sites in different tissues in a highly efficient way. It has enabled the identification of 6367 N-glycosylated protein sites.
Elemental and isotope analysis of the metals in ancient artefacts such as the prutah shown here sometimes can pinpoint the places where the metal was mined. This can be combined with historical sources to determine when the coin was likely struck. Archaeologists can use the evidence to identify or narrow date ranges of historical significance.
A new study from the Swedish medical university Karolinska Institutet presents a technique using LC-MS/MS that makes drug testing possible through exhaled air for the first time. By examining people who had received emergency care for an amphetamine overdose, the researchers found that in all cases there were traces of amphetamine and metamphetamine in the exhaled breath.
Scientists from Ruhr-Universität Bochum have used Raman micro-spectroscopy to distinguish, within seconds, healthy fertile and infertile sperm cells. The method has the potential for a novel fertility technology and a test scheme which does not only rely on morphological characteristics, but also utilises chemical signatures.
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- Atomic absorption
- Atomic emission
- Ion mobility
- Laser spectroscopy
- Mass spectrometry
- Near infrared
- NMR ESR EPR
- Related equipment
- RMs and standards
- Sample prep
- Separation science
- Surface analysis
- X-ray spectrometry