In the Tony Davies Column, we learn about “Automated detection of counterfeit drugs using multimodal spectroscopy and advanced web-based software platforms”. With the increase in trafficking of counterfeit medicines and other products, there is a need for definitive results from an on-site analyser useable by customs officers. The German authorities have commissioned the development of a multi-modal, transportable inspection system, including intelligent data processing and evaluation, for fast spectroscopic recognition of illicit drugs and counterfeit medicines. This is described in the column.
John Hammond updates us on “Reference materials: what’s new?”. The 2015 meeting of the ISO Committee on Reference Materials (ISO/REMCO) was held in June and significant developments in a number of standards that will ultimately affect all users of reference materials have taken place.
Kim Esbensen and Claas Wagner have gold on their minds. However, only to explain that “Sampling—is not gambling!”: the American “Gold Rush” of the late 19th Century is a good metaphor for the unrepresentative nature of grab sampling: something that you will soon realise is to be avoided in any sampling regime.
In situ spectroscopic methods such as infrared, Raman and UV/vis spectroscopy are powerful tools to gain insight into reaction mechanisms and catalyst actions in homogeneously catalysed reactions. These methods and combinations of them offer great potential for the real-time monitoring of reactions in the liquid phase, for mechanistic studies as well as process control and kinetics.
The question “What’s up doc?—High-precision isotopic analysis of essential metals in biofluids for medical diagnosis” is posed by Frank Vanhaecke and Marta Costas-Rodriguez. Research is under way as to the possibility of using high-precision isotopic analysis of metals in a biomedical context. The goal is to develop methods for medical diagnosis on the basis of isotopic analysis of mineral elements in biofluids, for diseases that can otherwise only be established at a later stage or via a more invasive method (e.g., a biopsy) and/or for prognosis purposes. Whilst this work is in a very early stage, it is known that various diseases have an influence on the uptake, metabolism and/or excretion of essential mineral elements and thus, can cause a difference in their isotopic composition in biofluids.
Karsten Hinrichs and Andreas Furchner describe “Infrared mapping spectroscopic ellipsometry”. Recent developments in fundamental and materials research have increased the value of mapping techniques such as ellipsometry. IR ellipsometry, since it operates in the mid-IR fingerprint region, provides complementary information on composition, structural properties and interactions
Tony Davies, Peter Lampen, Stephen Heller and Evan Bolton report on the future of the spectroscopic data collected as part of the EuroSpec programme. Its long-term preservation is being guaranteed through the PubChem Project of the US National Library of Medicine.
Kim Esbensen and Claas Wagner continue their study of “Heterogeneity—the root of all evil” in the Sampling Column. We would be most interested to hear readers’ views on our new column. Representative sampling is essential for most analyses to be relevant, and the column will move from its early theoretical introduction to practical solutions. Readers interested in learning more about the Theory of Sampling may be interested in the Proceedings of the 7th World Conference on Sampling and Blending which are now freely available at http://www.impublications.com/wcsb7.
In the Quality Matters Column, Peter Jenks reminds us about “BERM 14: it’s that time again!”. The latest in this line of conferences on Biological and Environmental Reference Materials is being held in the USA in October 2015.
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- The emerging use of magnetic resonance imaging to study river bed dynamics
- Graphene characterisation and standardisation via Raman spectroscopy
- Direct Analysis in Real Time mass spectrometry and its application for the analysis of polydimethylsiloxanes
- The use of inductively coupled plasma mass spectrometry to quantify chemical hazards in natural history collections: arsenic and mercury in taxidermy bird specimens
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- Atomic absorption
- Atomic emission
- Ion mobility
- Laser spectroscopy
- Mass spectrometry
- Near infrared
- NMR ESR EPR
- North America
- Related equipment
- RMs and standards
- Separation science
- South America
- Surface analysis
- X-ray spectrometry