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Researchers at the University of Konstanz, have for the first time successfully developed a novel on-line bioaffinity-electrospray ionisation (ESI) mass spectrometry (MS) approach, which enables the simultaneous label-free detection, identification and quantification of protein–ligand interactions. Combining the sam5 surface acoustic wave biosensor from SAW Instruments with ESI-MS has enabled the direct connection of protein–ligand dissociation constants (KD) analysis with their subsequent quantification and structural characterisation by MS.
The utility of Spatially Offset Raman Spectroscopy (SORS) in the early diagnosis of conditions such as the painful brittle bone disease is to be tested for the first time with hospital patients. The SORS instrument, the first to be commercially available, was delivered on Wednesday 3 November to the Institute of Orthopaedics and Musculoskeletal Science, University College London (UCL) on the Royal National Orthopaedic Hospital (RNOH) site in Stanmore, Middlesex, UK. The spectrometer will undergo testing to assess its usefulness with the long term aim of developing a specialist medical device to diagnose and detect early signs of diseases such as brittle bone disease and osteoarthritis.
AB SCIEX has expanded its commercial operations in Korea with a new direct sales organisation under AB SCIEX Korea. This expansion was made possible by an agreement with Life Science Korea (LSK) to transfer existing sales, service and marketing personnel to AB SCIEX, effective immediately.
Understanding the crystal chemistry of Nickel (Ni), in particular how the element is bonded to its surrounding elements, can improve its extraction process, making it greener and increasing the yield. Scientists from Diamond (the UK’s national synchrotron facility), in collaboration with mineralogists from the University of Barcelona, Spain, have combined measurements on the Microfocus Spectroscopy beamline (I18) and Raman spectroscopy to elucidate the chemistry and local environment of Ni in a Mn-oxyhydroxyde aggregate.
UK researchers will gain new insights into vital high tech engineering materials and novel pharmaceuticals thanks to the creation of the UK’s most powerful NMR device for solids now sited in a national research facility in the University of Warwick’s Centre for Magnetic Resonance.
Robert Huber from Ludwig-Maximilians-Universität (LMU) Munich has received a Starting Grant awarded by the European Research Council (ERC). The grant is worth 1.2 million Euros over a period of five years. The Starting Grants scheme is designed to support the work of outstandingly creative young investigators who are engaged in research at the forefront of their respective fields.
The first group of graduates of a new European Master's degree received their diplomas at the European Commission's Joint Research Centre (JRC) in Geel, Belgium. The degree, “Measurement Science in Chemistry”, was based on training initiatives developed by the JRC's Institute for Reference Materials and Measurements (IRMM).
Producing tightly focused beams of high energy X-rays, to examine everything from molecular structures to the integrity of aircraft wings, could become simpler and cheaper according to new research.
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- Infrared spectroscopic techniques for the non-invasive and rapid quality control of Chinese traditional medicine Si-Wu-Tang
- Synchrotron-based micro Fourier transform infrared mapping to investigate the spatial distribution of amorphous and crystalline calcium carbonate in earthworm-secreted calcium carbonate balls
- Spectroscopic evidences to understand the influence of marine environments on Built Heritage
- Infrared spectroscopy as a tool to study plant cuticles
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