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Tornado Spectral Systems has released the HyperFlux P.R.O. Plus process Raman analyser
Automated detection of counterfeit drugs using multimodal spectroscopy and advanced web-based software platforms
In the Tony Davies Column, we learn about “Automated detection of counterfeit drugs using multimodal spectroscopy and advanced web-based software platforms”. With the increase in trafficking of counterfeit medicines and other products, there is a need for definitive results from an on-site analyser useable by customs officers. The German authorities have commissioned the development of a multi-modal, transportable inspection system, including intelligent data processing and evaluation, for fast spectroscopic recognition of illicit drugs and counterfeit medicines. This is described in the column.
A new technique combines electron microscopy and synchrotron x-rays at Brookhaven Lab to track chemical reactions under real operating conditions.
Monitoring of catalytic reactions and catalyst preparation processes in liquid phase systems by combined in situ spectroscopic methods
In situ spectroscopic methods such as infrared, Raman and UV/vis spectroscopy are powerful tools to gain insight into reaction mechanisms and catalyst actions in homogeneously catalysed reactions. These methods and combinations of them offer great potential for the real-time monitoring of reactions in the liquid phase, for mechanistic studies as well as process control and kinetics.
Mobile µRaman and µ-BioRaman
Two portable Raman microscopes that are smaller than a portable sewing machine. The reduction in size has enabled shorter, more efficient light paths, reduction in laser power and faster scanning. Both systems offer multiple sampling handling modalities (microscope slide, cuvette, vial or syringe), a fast scanning PZT stage for Raman mapping and an optional battery pack. The µRaman interfaces with Bio-Rad’s Raman ID Expert database and the µ-BioRaman uses BioTools’ own library of protein spectra.
A hand-held Raman spectrometer with patented fluorescence mitigation that enables measurement of a wide range of raw materials. Duo LASER excitation with two wavelengths provides high sensitivity across the whole spectral range, and the instrument also features automated wavenumber calibration and automated measuring tip recognition. It is also certified as a class 1M laser product.
Portable Raman system with laser excitation at 785 nm and spectral range of 65–3200 cm–1 and resolution of ~4.5 cm–1 at 912 cm–1. Detection is by a high quantum efficiency CCD array, TE-cooled to –25°C.
Hand-held Raman analyser for plastics identification. Comes pre-loaded with a user-configurable library of over 45 plastics. Can identify light and dark plastics from all major families and sub-families, and the user can add their own plastics to the library. Two rechargeable batteries provide over 4 hours of operation.
Freedom mini Raman
OEM miniature Raman spectrometer, which is robust and almost athermal. It measures 61 × 64 × 19 mm and has a spectral range of 475–1100 nm with a resolution of 0.6 nm. It can be used with many different laser wavelengths covering the popular 532 nm, 785 nm and 830 nm.
Compact and easy-to-use dispersive laser Raman microscope designed for automatic use. It uses the same software interface as JASCO’s FT-IR spectrometers allowing IR users easily to transfer to the Raman system. It uses three lasers at 457 nm, 532 nm and 785 nm and a spectrograph resolution down to 0.7 cm–1. A new fluorescence rejection algorithm is also built into the instrument.
Combines a back-thinned CCD array detector with low stray light optical design, for applications including chemical catalysis and Raman analysis. A toroidal grating corrects optical aberrations and improves stray light performance, extending linear measurement range up to 3.0 OD. Stray light performance is 0.015% at 400 nm. The Maya LSL interfaces to a computer via its USB port and couples to Ocean Optics accessories.
The inVia confocal Raman microscope can now perform transmission Raman analysis, which provides greater flexibility. Transmission Raman is an attractive method for the fast, quantitative analysis of bulk material homogeneity, in applications such as tablet dose and blend uniformity.
Raman spectroscopy module that can be easily integrated with most upright microscopes from Nikon, Olympus, Leica or Carl Zeiss. Available in 532 nm, 633 nm and 785 nm versions. The module includes a high sensitivity linear array detector, power attenuation with laser safety interlock and user friendly software.
Fully automated, easy-to-use Raman imaging system that includes laser wavelength selection with subsequent adjustment of all associated spectrometer and microscope components to ensure optimised system performance. It also includes absolute laser power determination and regulation in 0.1 mW steps. The UHTS 600 is a new 600 mm focal length spectrometer designed for automated Raman imaging; spectral resolution is down to 0.1 rel cm–1 at 633 nm excitation.link.spectroscopyeurope.com/27-02-092
“In vivo Raman spectroscopy of skin” is Paul Pudney’s topic. The skin is a most important part of our bodies. There is great interest in studying it to help understand the many skin diseases we are prone to, including cancer, to develop skin care products and, increasingly, as an alternative route to administer pharmaceuticals instead of through the gut. Raman spectroscopy is an exellent tool to study these, and has particular advantages in its ability to do so in vivo.
Ibsen Photonics has announced the Freedom mini Raman spectrometer platform for integrators of analytical and process control instruments. The spectrometer is robust and almost athermal and can operate under demanding environmental conditions..
Application of Raman and photoluminescence spectroscopy for identification of uranium minerals in the environment
The “Application of Raman and photoluminescence spectroscopy for identification of uranium minerals in the environment” is described by Eric Faulques, Florian Massuyeau, Nataliya Kalashnyk and Dale Perry. Uranium forms a large number of compounds and complexes, and these are most helpful in the study of uranium, its chemistry and transport in the environment. Raman and photoluminescence spectroscopy provide complementary information and are powerful tools for direct speciation of uranium and identification of natural uranyl minerals relevant to the environment.
“Optical spectroscopy in therapy response monitoring: an awakening giant” by Arja Kullaa, Surya Singh, Jopi Mikkonen and Arto Koistinen looks at the important advances made by optical spectroscopy techniques, such as diffuse optical spectroscopic imaging (DOSI), Raman, diffuse reflectance and fluorescence spectroscopy, in changing how cancer is managed in patients. The ability to repeatedly monitor tumour dynamics to see how effective a particular treatment has been has enormous potential for us all.
Metrohm has introduced the Metrohm Instant Raman Analyser (Mira) which allows the analysis of any kind of heterogeneous and temperature-sensitive materials..
In this article, three real-life Raman quantitative and semi-quantitative analysis applications are discussed. These applications showcase the versatility of Raman spectroscopy and the potential impact that it can make in various industries.
Ocean Optics has introduced a new substrate for Raman spectroscopy applications.
Horiba Scientific has released a major update to its LabSpec 6 Raman spectroscopy software Horiba Scientific has released a major update to its LabSpec 6 Raman spectroscopy software. This features a new 3D surface and volume display mode, which is compatible with high-resolution confocal volume maps acquired with Horiba’s Raman microscopes. With full control of map rotation, transparency, filtering and slicing, the internal chemical structure of complex heterogeneous samples can be viewed. Topographic images form Horiba’s combined Raman-AFM and TERS systems can also be rendered by the module. Other additions include OneClick easy Raman acquisition, and PLS to the range of multivariate analysis routines.
SpectraPhysis has introduced the InSight DS+, a widely tunable ultrafast laser system.
Elucidating structural and compositional changes in plant tissues and single cells by Raman spectroscopic imaging
“Elucidating structural and compositional changes in plant tissues and single cells by Raman spectroscopic imaging” is the topic of the next article by Batirtze Prats Mateu, Barbara Stefke, Marie-Theres Hauser and Notburga Gierlinger. Understanding plant cells is important for the best use of plants in traditional and new applications. Raman spectroscopic imaging represents one of the best ways to unravel the molecular structure in the native environment of plant tissues.
“Emerging sampling approaches for Raman analysis of foods” by Nils Kristian Afseth, Matthew Bloomfield, Jens Petter Wold and Pavel Matousek describes how a number of instrumental developments are enabling Raman spectroscopy to find increasing applications in food analysis. They show how Spatially Offset Raman Spectroscopy (SORS) is being used to analyse quality parameters in salmon, including the content of fat, its fat composition and the content of carotenoids. Traditionally, the preserve of NIR spectroscopy, Raman may increasingly be used for the analysis of food and other biological matrices.
Report on the The Seventh International Conference of Advanced Vibrational Spectroscopy (ICAVS-7) held in Kobe, Japan.
Report on the 10th Confocal Raman Imaging Symposium 2013 in Ulm, Germany.
The single cell Raman spectrum (SCRS) enables cell probing and sorting to study phenotypes and ecophysiology of single cells and explore individual cells in situ in a label-free and non-destructive manner.
Highlighting the importance of utilising the polarisation properties of resonance Raman scattering in obtaining molecular information
In resonance Raman scattering (RRS), the amount of structural and chemical information deduced can be increased by analysing the polarisation of the inelastically scattered light, including the degree of molecular aggregation in bio-molecules in their natural environment.