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Tag: MRI Ordering

“Rheo-nuclear magnetic resonance spectroscopy: a versatile toolbox to investigate rheological phenomena in complex fluids” is Claudia Schmidt’s topic. Rheology is an important science, and NMR has a number of uses within it. However, challenges remain for the simultaneous measurement of rheological and NMR parameters.

Bruker has announced the introduction of the Icon, an easy-to-use 1 Tesla desktop MRI scanner that combines simplicity with compact dimensions, bringing preclinical magnetic resonance imaging within reach of a broader range of molecular imaging laboratories. It features a cryogen-free permanent magnet and high-performance Avance III spectrometer technology with ParaVision preclinical MRI software, The compact, shielded magnet with its small footprint results in an easy to site and install MRI system with very low running costs. It has zero magnetic fringe field, enabling safe location of the system in any facility and for use by any operator. No additional magnetic or RF shielding is required for implantation in the lab.

Bruker AXS
Issue: 22-05
RSN: 111

Tags: MRI

Through a combination of remote instrumentation, JPEG-style image compression algorithms and other key enhancements, Alexander Pines and members of his research group have been able to use Nuclear Magnetic Resonance (NMR) spectroscopy and Magnetic Resonance Imaging (MRI) to image materials flowing through microfluidic “lab-on-a-chip” devices and zoom in on microscopic objects of particular interest with unprecedented spatial and time resolutions.

In two studies published today in the journal Drug Testing and Analysis, UK and Swiss research teams reveal two techniques proven to identify dissolved cocaine in bottles of wine or rum. These tools will allow customs officials to quickly identify bottles being used to smuggle cocaine, without the need to open or disturb the container.

The School of Chemistry at Leeds University provided an ideal venue for the 2010 Royal Society of Chemistry NMR Discussion Group Postgraduate meeting. This one-day conference has now become an annual event, comprising talks and posters presented by early career researchers, giving them an opportunity to showcase their research in a friendly and informal atmosphere. On this occasion, overview presentations were also given by leading experts in their fields. Delegates included established scientists and group leaders from both academia and industry, providing a supportive and stimulating environment for all those presenting.

The recipients of the 2010 European Magnetic Resonance Awards are John R. Griffiths (Basic Sciences) for his contributions to the applications of magnetic resonance spectroscopy in oncology, and Stefan Neubauer (Medical Sciences) for his contributions to anatomical and functional cardiovascular magnetic resonance imaging and spectroscopy.

Magnetic resonance (MR) spectroscopy may in the future be able both to pinpoint the precise location of prostate cancer and to determine the tumour's aggressiveness, information that could help guide treatment planning. In Science Translational Medicine (doi: 10.1126/scitranslmed.3000513), Massachusetts General Hospital (MGH) researchers report how spectroscopic analysis of the biochemical makeup of prostate glands accurately identified the location of tissue confirmed to be malignant by conventional pathology.

Espinosa Alonso, a chemist from Utrecht University, The Netherlands, used four different spectroscopic techniques to study catalysts in the course of their preparation: UV-vis-NIR-microspectroscopy, IR microspectroscopy, magnetic resonance imaging (MRI) and tomographic energy dispersive diffraction imaging (TEDDI). Whilst MRI and TEDDI are already frequently used in other research fields, but they are not commonly used to study the preparation of catalysts.

Magnetic resonance imaging can now be combined with conventional spectroscopic measurements with PharmaSense, an integrated MR imager and USB-4 compatible dissolution flow cell system from Oxford Instruments Molecular Biotools. It will allow drug formulation chemists to determine ways in which tablets and capsules hydrate, swell, erode and release their active ingredients, enabling a deeper insight into the mechanism of drug release, potentially improving drug efficacy and patient compliance. It is a stand alone instrument with a minimal footprint which allows for single user operation and provides software for both data acquisition and analysis.Oxford Instruments MolecularIssue: 20/05 RSN:

Tags: MRI

Peter A. RinckEuropean Magnetic Resonance Forum (EMRF) Foundation, WTC, BP 255, F-06905 Sophia Antipolis Cedex, France

In 1946, two scientists in the United States, independently of each other, described a physicochemical phenomenon that was based upon the magnetic properties of certain nuclei in the periodic system. This was “nuclear magnetic resonance”, for short “NMR”. The two scientists, Felix Bloch and Edward M. Purcell were awarded the Nobel Prize in Physics in 1952.

Researchers at Dartmouth College and Dartmouth Medical School, Hanover, NH, USA) have devised a new, potentially more accurate method for diagnosing breast cancer. They use MRI to produce an image of the breast and highlight potential cancerous sites. NIR spectroscopy is then used on these sites, giving information on haemoglobin levels, oxygen saturation and water content. These are indicators of cancerous tissue.

Their work is published in Optics Letters, doi: 10.1364/OL.32.000933

Bruker Daltonics has received a Product Innovation Award from Frost & Sullivan in recognition of Bruker’s contributions to a broad array of mass spectrometry technologies and for its commitment to the growing field of proteomics.