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WITec has introduced a line extension of the alpha300 microscope series. Building on the system's inherent modularity, several new microscope versions have been added in order to meet all diverse and multi-faceted customer requirements.
The inability to have children can cause great heartache for many couples, with infertility affecting at least one-in-six couples in Britain and one-in-eight in the United States. The most common cause is male infertility, usually characterised by sperm with little or no mobility. One treatment commonly used in these cases is in vitro fertilisation (IVF). This involves injecting sperm into the egg in a laboratory.
Scientists from Ruhr-Universität Bochum have used Raman micro-spectroscopy to distinguish, within seconds, healthy fertile and infertile sperm cells. The method has the potential for a novel fertility technology and a test scheme which does not only rely on morphological characteristics, but also utilises chemical signatures.
The location of metal complexes within living cancer cells has been accurately determined using Raman microscopy. The researchers have thus gained new insights into the mechanism of action of metal-containing drugs, to which they ascribe great potential capacities, e.g. in the treatment of cancer. These findings are of fundamental significance and are thus featured as a VIP (very important paper) in the current edition of Angewandte Chemie.
Patrik Johanssona and A.M.C. DaviesbaApplied Physics, Chalmers University of Technology, SE-41296 Göteborg, SwedenbNorwich Near Infrared Consultancy, 75 Intwood Road, Cringleford, Norwich NR4 6AA, UK. E-mail: firstname.lastname@example.org
In last year’s August/September issue of Spectroscopy Europe1 I wrote a column about my “discovery” of computational chemistry and asked if anyone was interested. A satisfying number of readers answered the on-line survey with very positive comments but none more so than Patrik Johansson who e-mailed me about his delight with the column and to assure me that there was “indeed a bunch of scientists out there that do work on IR (and Raman) using both experimental and computational techniques—I am one of them”! This column is the first result of the ensuing e-mail conversation and is due to Patrik. I remain excited by the possibilities of computational chemistry particularly as Patrik thinks that an approach to NIR spectroscopy is indeed possible.Tony Davies
Jean-Philippe Echarda and Loïc BertrandbaLaboratoire de recherche et de restauration, Musée de la musique, Cité de la musique, 221 avenue Jean Jaurès, 75019 Paris, France. E-mail: email@example.comIPANEMA, synchrotron SOLEIL, Saint-Aubin, 91192 Gif-sur-Yvette cedex, France
For the past two centuries, the nature of the varnishes coating historical instruments has been a much debated subject. Focusing in particular on the varnishes used for coating violins made by the Italian instrument-maker Antonio Stradivari, numerous hypotheses have been raised by instrument-makers, experts, musicians and chemists, without reaching a general understanding of the ancient varnishing techniques. A few years ago, we decided to work on this topic using several complementary approaches for materials characterisation and study of historical sources (ancient varnish recipes, etc.).
ChemImage will present the results of an ingredient-specific particle sizing (ISPST) study on a combination metered dose inhaler product at Respiratory Drug Delivery (RDD) 2010 (www.rddonline.com). This conference takes place from 25 to 29 April in Orlando, Florida, USA, and covers current biological and pharmaceutical issues related to nasal and respiratory drug delivery.
Using a novel hybrid sensor system, based on Shamrock spectrometers and high performance intensified CCD detectors supplied by Andor Technology, Spanish scientists have been able to use both Raman and Laser-Induced Breakdown Spectroscopy (LIBS) simultaneously for the instant, remote standoff analysis of explosive materials.
Jasco’s NRS-5000/7000 series of Raman spectrometers can integrate as many as eight excitation lasers (nine wavelengths) from the UV to the NIR, with automated laser/Raman scattering path alignment, automated grating and laser selection and up to two detectors. The NRS-5100/5200 instruments feature a 300 mm spectrograph and three selectable gratings. The NRS-7100/7200 instruments include a 500 mm spectrograph and up to four selectable gratings. The NRS-5200 and NRS-7200 instruments offer a dual-grating, low wavenumber measurement unit for optimised Raleigh rejection and Raman spectra down to 10 cm–1. The NRS-5000/7000 instruments offer high-speed imaging capability using the Software Programmable Raman Integration System (SPRIntS) for rapid scanning and sample imaging capabilities. The Verti-Scan capability ensures a consistent confocal sample excitation capability to obtain undistorted 3D images, without the use of an automated X-Y-Z sample stage. The Dual Spatial Filtering capability reduces sample fluorescence while enhancing spatial resolution.
Ahura Scientific, Inc., has announced the close of Thermo Fisher Scientific Inc.’s acquisition of the company. The acquisition expands Thermo Fisher’s technology portfolio with a suite ofportable spectrometers.
Ahura Scientific, now part of Thermo Fisher Scientific, have introduced the FirstDefender RM and FirstDefender RMX, rugged handheld Raman spectrometers for use by first responders, homeland security, military, law enforcement and forensic chemistry personnel. The instruments allow users to quickly identify unknown chemicals from a vast sample library of more than 10,000 pure substances including: explosives, toxic industrial chemicals (TICs), toxic industrial materials (TIMs), chemical warfare agents (CWAs), white powders, narcotics, precursors and more. Ahura Scientific’s chemometric algorithms enable automatic mixture analysis with every scan. Both instruments are certified to US military’s MIL-STD 810F specifications for ruggedness including drop, shock, vibration and operation in extreme temperatures.
Thermo Fisher Scientific has signed a definitive agreement to acquire Ahura Scientific, manufacturer of portable spectrometers, for $145 million in cash plus the potential for an earn-out payment based on the achievement of certain 2010 financial targets. The acquisition expands Thermo’s portfolio of portable instruments; they already have a line of portable XRF analysers. www.thermofisher.com, www.ahurascientific.com
Sword Diagnostics has been awarded a US Patent titled Method and Apparatus for Detection of Biological Organisms using Raman Scattering. The patent covers the core technology which focuses on improved sensitivity. www.sworddiagnostics.com
Horiba has announced the construction of a new research facility and European headquarters on the campus of the École Polytechnique in Paris. The new centre will give Horiba access to a pool of innovative technologies, resources and personnel from nearby academic, government and commercial research centres. It is due to open in late 2011. www.horiba.com/uk/scientific
ChemImage has been selected for $2 million of US defence funding for further development of the Eye-Safe Stand-Off Fusion Detection of chemical, biological, explosive and improvised explosive device threats. The system will combine multiple sensing technologies, including Raman and shortwave infrared chemical imaging. www.chemimage.com
Newport Corporation has introduced a new coherent anti-Stokes Raman scattering optimised supercontinuum generation fibre device, the SCG-800-CARS, which has been designed for use with 800 nm femtosecond lasers and contains 12 cm non-linear crystal fibre with zero dispersion points at ~775 nm and 945 nm.
Researchers at the University of St Andrews have developed a powerful technique that could allow earlier cancer detection. In a joint venture between the Schools of Physics & Astronomy and the Bute Medical School, the St Andrews researchers have advanced new technology that relies on Raman spectroscopy.