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Tag: Raman Ordering

Bruker has announced the launch of its N8 Neos Santerra micro analysis system that combines Raman spectroscopy and atomic force microscopy on a single optical microscope platform.

The judicious use of a state-of-the-art imaging method enables researchers to capture structural snapshots of complex molecules as they participate in chemical reactions, revealing the sequence of specific atomic motions that lead to chemical change. It’s thought the approach, described in Nature (doi: 10.1038/nature08527), can be used more widely to improve our understanding of important chemical transformations.

Tags: Raman

Scientists at Queen’s University Belfast are developing a Raman spectroscopy-based sensor to detect chemical agents and illegal drugs which will help in the fight against the threat of terrorist attacks. Special gel pads will be used to “swipe” an individual or crime scene to gather a sample which is then analysed by the Raman instrument that can detect the presence of chemicals within seconds. This will allow better, faster decisions to be made in response to terrorist threats.

Tags: Raman

Princeton Instruments has introduced an intensified CCD camera, the PI-Max 3. It is a fully integrated camera that provides a combination of frame rate, gating and low-noise capabilities for improved performance in applications such as fluorescence lifetime imaging measurements, laser-induced breakdown spectroscopy, pulsed Raman spectroscopy, nanotechnology studies and plasma diagnostics. Features include a built-in timing generator, the SuperSynchro, which makes setting up complex time-resolved imaging experiments easy, SyncMaster technology helps reduce lab clutter by eliminating the need for an external timing generator, it can be configured with either a 1024 × 1024-pixel interline transfer CCD or a 1024 × 246-pixel full-frame CCD and it also features photocathode cooling for ultra-low light or single-photon imaging as well as special readout modes for single-shot measurements and particle imaging velocimetry applications.

Princeton Instruments Acton Issue: 21/05 RSN: 112 More information via

ST Japan have added 2100 new Raman spectra to their existing collection and now offer more than 10,000 spectra, including polymers and additives, solvents, pharmaceuticals, packaging materials, forensics and minerals. All spectra have been taken from samples of high purity, contain extensive sample information and have been reviewed by trained spectroscopists. The databases are available in the common spectra format and can be used directly with the search software of the users instrument, enabling them to continue working in their usual software environment and improve search results.

S T Japan-Europe Issue: 21/05 RSN: 121 More information via
Tags: Raman

Ahura Scientific has announced an upgrade to the language capabilities of its TruScan hand-held Raman spectrometer, designed for the pharmaceutical and consumer health industries. With the introduction of TruScan 1.3.0, the graphical user interface is accessible in German as are the user manuals and instrument administration tools.

Ahura Scientific Issue: 21/05 RSN: 120 More information via
Tags: Raman

The new DSC-Raman system from PerkinElmer combines thermal analysis with Raman spectroscopy to provide greater insight into material changes at a molecular level. It combines the double furnace DSC 8500 with the RamanStation 400 spectrometer, enabling simultaneous analysis of chemical and structural information from the spectrometer and correlating it with the calorimetric data of the DSC. Tests using the hyphenated techniques have given greater insight into polymer crystallisation, drug–carrier interactions, curing and polymorphic changes.

Renishaw has enhanced the capabilities of its inVia microscope which now offers remote system diagnosis and control of key system functions such as laser wavelength change, rapid switching between viewing modes, automated system optimisation and validation, the ability to queue multiple measurements and measurement templates that enable non-expert users to apply identical experimental conditions continuously. The microscopes now offer complete automation, remote control, large area imaging and faster operation.

Renishaw Plc Issue: 21/05 RSN: 118 More information via

Dr Neil Lewis, Technical Director of Malvern Instruments, is to receive the Anachem Award of the Detroit Section of the American Chemical Society at this year’s FACSS in October.

{rokbox title=|WITec's new HQ|}images/stories/news/witecbuilding.jpg{/rokbox}WITec has moved to its new headquarters building in Ulm, which has customised production facilities, seminar rooms and office space on four floors covering more than 1900 m2.
Tags: Raman

Iain A. Larmour, Jennifer P.E.D. Gray and Steven E.J. BellInnovative Molecular Materials Group, School of Chemistry and Chemical Engineering, Queen’s University Belfast, Belfast, BT9 5AG, UK


Interest in Raman spectroscopy as an analytical technique that can be applied in a wide variety of fields continues to increase. The main reason for this interest is that no special sample preparation is required. However, the Raman signal is typically very weak, with only one in every 106–108 photons being scattered. This has driven the development of several enhancement techniques, e.g. Resonance Raman (RR), Surface Enhanced Raman Spectroscopy (SERS) and Surface Enhanced Resonance Raman Spectroscopy (SERRS), which can be used for dilute samples.

The development of the Raman imaging spectrograph came from the need for combining high light throughput, distortion-free performance and polarisation-free optical design. These requirements, together with the small footprint of the device, good image quality and high spectral resolution were achieved with the fully transmissive design used in the Specim ImSpector series of imaging spectrographs, which are available for several standard wavelength ranges from 500 nm up to 1000 nm for use with different types of excitation lasers.

Specim Spectral Imaging Ltd Issue: 21/03 RSN: 113 More information via
Tags: Raman

The innoRAM high-resolution Raman spectrometer, manufactured by B&WTek, is now available from Pacer. It is a portable, laboratory-grade system which includes a back-thinned 2-D-summed CCD linear array of 2048 pixels, TE-cooled to an operating temperature of –20°C and features 785 nm Cleanlaze technology. A choice of 532 nm or 785 nm narrow line width wavelength stabilised lasers is available, with 40 mW and 300 mW, respectively, exiting via the fibre port. The package includes laser safety goggles and user- controlled laser power via software. A wide range of probes and accessories is available.Pacer International LtdIssue: 21/03 RSN:

Tags: Raman

Malvern Instruments has launched a 64-bit edition of the ISYs chemical imaging data analysis software which has applications across many technologies. It provides a single platform that supports the import of MIR, NIR and Raman imaging and mapping data files from a variety of vendors. It includes all the tools needed to understand chemical imaging data in spectral and spatial dimensions simultaneously.Malvern Instruments LtdIssue: 21/03 RSN:

Andor Technologies has launched its new OEM-dedicated iVac spectroscopy detector range. Designed around its UltraVac vacuum package, this price-performance camera offers a rugged and compact package. The company's Software Development Kit enables easy integration of the USB2.0 device into the likes of Raman bench top stations or spectral engines working in challenging ­environments.

Andor Technology Ltd Issue: 21/01 RSN: 110

Manufactured by CDI Pharma, the Shakti “process ready” Raman analyser system features a high- resolution, wide spectral range, high sensitivity and auto-calibration spectrometer with a built-in self-referencing probe, adjustable working distance and adjustable sample spot size. Applications include raw material ID, coating content, polymorph screening, measuring drug concentration in dissolution media, quantitating solid phase transformations in situ and analysing solid-phase transformations during fluidised bed drying.

CDI Pharma Issue: 21/01 RSN: 123
Tags: Raman

Renishaw has developed its Streamline Plus Raman imaging system, which combines hardware, software and firmware to improve data collection, visualisation and processing. The combination of line focus, for minimal sample damage, high-speed encoded stage and synchronised readout of the CCD detector enables images to be collected rapidly and at variable spatial resolution. There are no limits to the image area dimensions imposed by the objective field of view, therefore enabling adaptability and eliminating the need to stitch images together for large area coverage, resulting in artefact-free results. Integration of WiRE 3.1 software offers many benefits. Regions of interest are simple to set up using optical micrograph montages, experiments can be queued and chemical images can be viewed and manipulated during acquisition, whilst a suite of visualisation and chemometric tools are available to process and analyse the collected data. The software also offers additional features including full support for multiple detectors, automatic spectrometer configuration for “hands-free” excitation wavelength changes and enhanced integration tools for third party products.

Renishaw Plc Issue: 21/01 RSN: 122
Tags: Raman Imaging

Scientists at the University of Edinburgh, UK, have developed a technique using Raman spectroscopy to test the quality of sperm before it is used for in vitro fertilisation (IVF) and increase the chances of conception. Dr Alastair Elfick, lead scientist on the project, explained: “in natural conception the fittest and healthiest sperm are positively selected by the arduous journey they make to the egg. What our technology does is to replace natural selection with a DNA-based ‘quality score’.” This can then be used to decide whether the sperm is healthy enough to be used to fertilise an egg as part of the IVF treatment.

The sperm are captured in two highly focussed beams of laser light, optical tweezers, and then the DNA of an individual sperm can be analysed from its Raman spectrum. The research is currently in a pre-clinical phase, and if successful could be available to patients in the next five to ten years.

Tags: Raman

Researchers at the Humboldt-Universität zu Berlin, Germany, have reported in Analytical Chemistry (doi: 10.1021/ac801791a) an advance toward development of technology that could underpin automated, real-time systems for identifying specific kinds of plant pollen circulating in the air.

Scientists have identified chemical structures in pollen, shown covering the face and legs of a Marmelade fly, that could help provide a real-time pollen detection and warning system to help allergy sufferers. Credit: André Karwath

Janina Kneipp and colleagues explain that current pollen counts and allergy warnings are based on visual identification of the specific kind of pollen by examining pollen grains under a microscope. That procedure takes time, making it impossible for allergy-sufferers to know the kinds of pollen that are airborne on an hour-by-hour basis. The researchers describe using Raman spectroscopy to identify chemical structures in pollen grains that distinguish oak and maple pollen, for instance, from maple and other kinds. They obtained these chemical “signatures” for 15 different kinds of tree pollen.

Tags: Raman
Renishaw has signed an OEM agreement with NT-MDT whereby NT-MDT will sell, install and support special inVia Raman systems for integration with its Ntegra AFM.,
Tags: Raman