fNIRS is a non-invasive optical technique that measures oxygen levels in the brain to chart neurological activity. The difference between oxygenated haemoglobin and deoxygenated haemoglobin can be used as a correlate of brain activity. Using fNIRS, this difference in blood oxygen level is determined using a relative spectroscopic measurement at two NIR wavelengths.
One of the main techniques for measuring and monitoring mental activity, functional near infrared spectroscopy (fNIRS), can often be impaired because a person’s hair gets in the way. A team of researchers at the University of Texas at Dallas and the University of Texas at Arlington have developed a “brush optrode”, which provides increased sensitivity with fibre tips designed to thread through hair to enhance scalp contact.
Details of the device will be presented at the Optical Society’s (OSA) 94th annual meeting, Frontiers in Optics (FiO) 2010, at the Rochester Riverside Convention Center in Rochester, NY, from 24 to 28 October 2010.
“Using light to measure a person’s thinking pattern has numerous advantages over EEGs, including ease of use, reliability, cost, portability and MRI compatibility,” says Duncan MacFarlane, professor of electrical engineering in the Erik Jonsson School of Engineering and Computer Science at the University of Texas at Dallas. “The conventional fibres used in fNIRS systems terminate in a large, flat bundle, and it is easy for a patient’s hair to get in the way and block the signal,” he explains. “So we developed a new tip for the fNIRS fibres—a brush optrode that slides the fibres between the hair follicles. Signal levels increase three- to five-fold, and patients report that the brush optrode is considerably more comfortable than the conventional fibre ends. And the brush optrode is easier to set up, which saves time and money.”
This research is expected to open the door to portable, easy-to-use, high-density optical scanning of brain activity. For example, the University of Texas researchers’ work focuses on the imaging of changes in cortical plasticity as a function of impairment severity in children with cerebral palsy. According to Georgios Alexandrakis, a member of the UT Arlington research team, the newly developed optrodes could also be potentially useful to a variety of fNIRS projects, including the evaluation of recovery from stroke, changes in brain activity in Alzheimer’s patients, the perception of pain, and for assessing developmental changes in normal and impaired paediatric populations.
The presentation, “Improved fNIRS Using a Novel Brush Optrode” is at 12:30 pm on Tuesday, 26 October 2010.